Optical coherence tomography contrast enhancement using spectroscopic analysis with spectral autocorrelation
نویسندگان
چکیده
منابع مشابه
Contrast enhancement in optical coherence tomography
Molecular imaging is a powerful tool for studying disease progression and potential therapies in animals. Optical coherence tomography (OCT) is an important biomedical imaging modality, filling the niche between ultrasound and microscopy. However, OCT suffers from an inherent lack of molecular contrast (the ability to distinguish a molecule of interest from others). This is because the scatteri...
متن کاملSpectroscopic optical coherence tomography.
Spectroscopic optical coherence tomography (OCT), an extension of conventional OCT, is demonstrated for performing cross-sectional tomographic and spectroscopic imaging. Information on the spectral content of backscattered light is obtained by detection and processing of the interferometric OCT signal. This method allows the spectrum of backscattered light to be measured over the entire availab...
متن کاملNonlinear optical contrast enhancement for optical coherence tomography.
We present a new interferometric technique for measuring Coherent Anti-Stokes Raman Scattering (CARS) and Second Harmonic Generation (SHG) signals. Heterodyne detection is employed to increase the sensitivity in both CARS and SHG signal detection, which can also be extended to different coherent processes. The exploitation of the mentioned optical nonlinearities for molecular contrast enhanceme...
متن کاملAnalysis of peripapillary atrophy using spectral domain optical coherence tomography.
OBJECTIVE To study retinal morphologic changes around the optic disc in patients with peripapillary atrophy (PPA) with high-resolution spectral domain optical coherence tomography (SD OCT). DESIGN Cross-sectional, retrospective analysis. PARTICIPANTS A total of 103 eyes of 73 patients with PPA and 21 eyes of 12 normal patients seen at the New England Eye Center, Tufts Medical Center, betwee...
متن کاملMobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography.
Phase variance-based motion contrast is demonstrated using two phase analysis methods in a spectral domain optical coherence tomography system. Mobility contrast is demonstrated for an intensity matched Intralipid solution placed without flow within agarose wells. Vasculature oriented transversely to the imaging direction has been imaged for 3-4 dpf in vivo zebrafish using the phase variance co...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Optics Express
سال: 2004
ISSN: 1094-4087
DOI: 10.1364/opex.12.005487